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KMID : 0438420120190020153
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Korean Journal of Bone Metabolism
2012 Volume.19 No. 2 p.153 ~ p.158
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A Case of Cushing Syndrome Diagnosed by Recurrent Pathologic Fractures in a Young Woman
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Han Ju-Young
Lee Jung-Jin
Kim Gyung-Eun
Yeo Jin-Yeob
Kim So-Hun
Nam Moon-Suk
Kim Yong-Seong
Hong Seong-Bin
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Abstract
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Cushing’s syndrome is characterized by central obesity, fatigability, weakness, amenorrhea, hirsutism, edema, hypertension, impaired glucose tolerance, and osteoporosis due to excessive production of steroids. Cushing’s syndrome is an important cause of secondary osteoporosis. Patients with Cushing’s syndrome have a high incidence of osteoporotic fractures. At least, 30-50% of patients with Cushing’s syndrome experience fractures, particularly in the vertebral body. And it is consistent with the 50% prevalence of osteoporosis in patients with Cushing’s syndrome. However, reports of multiple pathological fractures in young patients with Cushing’s syndrome are rare. Thus, we describe the case of a 26-year-old woman with Cushing’s syndrome accompanied with recurrent multiple osteoporotic fractures and being treated by parathyroid hormone. Careful consideration for the possibility of Cushing’s syndrome will be necessary in case of young patients with a spontaneous multiple compression fractures in spine.
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KEYWORD
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Cushing syndrome, Osteoporotic fractures
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